Research findings show that gold nanoparticles have the potential to be used as coatings for protein-repellent materials in biomedical applications. Inhibiting unspecific blood protein adsorption is of crucial importance for blood-contacting implant devices, e.g. vascular grafts, stents, artificial joints, and others, as a preventive strategy for bacterial biofilm formation. The ability of polyvinylpyrrolidone (PVP)-stabilised gold nanoparticle coatings to inhibit blood protein adsorption was evaluated by studying time-resolved solid–liquid interactions of the coatings with the model blood protein bovine serum albumin (BSA).
